宋智勇，男，中共党员，副教授，理学博士，近年来主要围绕智能化纳米材料的设计与可控制备，用于药物的定点、可控释放，以耐药性细菌为研究对象，开展纳米化学生物学效应研究。目前以第一作者或通讯作者在Nature Communications，Advanced Functional Materials, Small，Biomaterials，Chemical engineering journal，ACSAppliedMaterials &Interfaces，Environmental Science: Nano，Chemical Communications等国际学术期刊上发表论文13篇，其中影响因子大于10的论文5篇，大于5的论文9篇。目前主持国家自然科学，华中农业大学校自主创新基金等多项基金。

研究领域

（1）纳米材料的设计与可控制备，用于药物分子的定点、可控释放；

（2）无抗生素纳米载药系统的构建及其针对超级细菌感染治疗；

科研项目

（1）国家自然科学基金委员会，青年项目，21807036，跨血脑屏障CRISPR/Cas13a递送系统的构建及其对狂犬病的治疗研究，2019年01月至2021年12月，27.5万，在研；

（2）华中农业大学自主创新基金，培育专项，2662020LXPY007，细胞膜仿生纳米平台构建及其用于幽门螺旋杆菌靶向治疗研究，2020年05月至2023年4月，21万，在研；

（3）华中农业大学，教师启动基金，纳米材料介导的单克隆抗体细胞内递送及协同抗病毒治疗，2016年09月至2019年8月，15万，结题。

近5年代表性论文

（1）YangWu^#,ZhiyongSong^#, HuajuanWang, HeyouHan* Endogenous stimulus-powered antibiotic release from nanoreactors for a combination therapy of bacterial infectionsNature communications, 2019, 10 (1), 1-10.

（2）ZhiyongSong^#, YangWu^#, QiCao, HuajuanWang, XiangruWang, HeyouHan*.pH‐Responsive, Light‐Triggered on‐Demand Antibiotic Release from Functional Metal–Organic Framework for Bacterial Infection Combination Therapy,Advanced Functional Materials, 2018, 28 (23), 1800011.

（3）YangWu, GuiyunDeng, KaiJiang, HuajuanWang,ZhiyongSong*, HeyouHan*. Photothermally triggered nitric oxide nanogenerator targeting type IV pili for precise therapy of bacterial infections,Biomaterials, 2020, 120588.

（4）HuajuanWang^#, JinZhang^#,ZhiyongSong^#, YongliMu, MF Foda, YangWu, HeyouHan.An intelligent platform based on acidity-triggered aggregation of gold nanoparticles for precise photothermal ablation of focal bacterial infection,Chemical Engineering Journal, 2020, 127076.

（5）ZhiyongSong, XiaoyuWang*, GenxinZhu, QinggongNian, HangyuZhou, DongYang, ChenfengQin, RuikangTang*.Virus Capture and Destruction by Label‐Free Graphene Oxide for Detection and Disinfection Applications,Small, 2015, 11 (9-10), 1171-1176.

（6）ShuojunLi^#,ZhiyongSong^#, CaiyunLiu, XiaolinChen*, HeyouHan*.Biomimetic Mineralization-Based CRISPR/Cas9 Ribonucleoprotein Nanoparticles for Gene Editing,ACS Applied Materials & Interfaces, 2019, 11 (51), 47762-47770

（7）JunMa^#,ZhiyongSong^#, JianhongYang, YouningWang, HeyouHan*.Cobalt Ferrite Nanozyme for Efficient Symbiotic Nitrogen Fixation via Regulating Reactive Oxygen Metabolism,Environmental Science: Nano, 2020.

（8）ZhiyongSong^#, YangWu^#, HuajuanWang, HeyouHan*. Synergistic antibacterial effects of curcumin modified silver nanoparticles through ROS-mediated pathways,Materials Science and Engineering: C, 2019, 99, 255-263.

（9）ZhiyongSong, LongLiu, XiaoyuWang, YongqiangDeng, QingongNian, GuanchuanWang, ShunyaZhu, XiaofengLi, HangyuZhou, TaoJiang, XurongXu, RuikangTang*, ChenfengQin*. Intracellular delivery of biomineralized monoclonal antibodies to combat viral infection,Chemical Communications, 2016, 52(9): 1879-1882.